10 Closest Anime Siblings Who Prove Family Is More Than Blood

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  • Tanjiro and Nezuko Kamado from Demon Slayer: Kimetsu no Yaiba are a perfect example of siblings who support and protect each other unconditionally.
  • Hachiman and Komachi Hikigaya from My Teen Romantic Comedy SNAFU rely on each other despite Hachiman's cynical attitude and refusal of help from others.
  • Yui and Ui Hirasawa from K-On! show that sometimes the younger sibling can be more mature and responsible, as Ui takes care of Yui while looking up to her.
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Given the medium's broad range of diverse genres and themes, it should be no surprise that all kinds of relationships are depicted in anime, including some anime siblings that have become so iconic that fans instantly recognize their bond.

In anime, much like in life, a relationship between siblings can take a variety of forms. For instance, some are more distant or indifferent towards each other's existence, while others stand together and support each other under any circumstances. Whether they faced deadly foes, impossible situations, or any other struggles, these brothers and sisters always had each other's backs, protecting and encouraging each other to achieve their respective goals.

10 Tanjirou & Nezuko Kamado (Demon Slayer: Kimetsu no Yaiba)

Produced by ufotable and Based on the Manga by Koyoharu Gotouge

The journey of Tanjirou and Nezuko Kamado in Demon Slayer: Kimetsu no Yaiba begins with tragedy. When Tanjirou, who was away selling charcoal, returns, he witnesses his entire family slaughtered by a demon, save for his sister, who was turned into one. Although Nezuko is initially quick to attack, she then comes to her senses and remembers her bond with her brother.

Growing up in a poor yet loving family, it is clear that the siblings always cared deeply for each other. Tanjirou and Nezuko are both normally calm and gentle, but they are also highly protective of each other and would attack anyone who dares to harm their beloved sibling.

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9 Hachiman & Komachi Hikigaya (My Teen Romantic Comedy SNAFU)

Produced by Brain's Base and Based on the Light Novel by Wataru Watari & Ponkan 8

My Teen Romantic Comedy SNAFU - Hachiman & Komachi Hikigaya buying food

My Teen Romantic Comedy SNAFU follows Hachiman Hikigaya, a cynic and nihilistic high school student who genuinely believes that everyone who claims to experience youthful joy is a self-deceiving liar. However, his attitude and outlook on life slowly begin to change as he is forced to join the Volunteer Service Club, helping other students in need.

Yet, because of his prideful and independent personality, he typically refuses help from others, never relying on anyone, except for his younger sister, Komachi. Because their parents were rarely home, Hachiman and Komachi had to take care of each other and grew to genuinely care and trust each other, although Komachi sometimes teases Hachiman.

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8 Yui & Ui Hirasawa (K-On!)

Produced by Kyoto Animation and Based on the Manga by Kakifly

K-On! follows Yui Hirasawa, a carefree girl who decides to join the Light Music Club on a whim, despite not being able to play any instruments. Yet, under the threat of disbandment, the club is desperate for new members and the other girls are more than willing to have Yui join them, help her learn guitar, and play together.

In fact, as part of the club, Yui even dedicates one of her first written songs to her sister, Ui. The two sisters care for each other deeply, although, ironically enough, it is Ui, the younger sister, who often proves to be more mature and responsible, by taking care of Yui.

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7 Sora & Shiro (No Game, No Life)

Produced by Madhouse and Based on the Light Novel by Yuu Kamiya

No Game, No Life revolves around two inseparable step-siblings, Sora & Shiro, who spend all of their time playing and dominating video games under the nickname "Blank". One day, they are suddenly summoned to a different world, named Disboard, by a god named Tet, who takes an interest in their aptitude for games.

Here, everything is decided through games, and it is now up to Sora and Shiro to save humanity. Although both of them are extremely capable and intelligent, they are so close that being separated interferes with their ability to perform at normal standards. Though Sora and Shiro can hardly function by themselves, together they are unbeatable.

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6 Sakuta & Kaede Azusagawa (Rascal Does Not Dream of Bunny Girl Senpai)

Produced by CloverWorks and Based on the Light Novel by Hajime Kamoshida & Keiji Mizoguchi

Rascal Does Not Dream of Bunny Girl Senpai - Sakuta comforts Kaede

The main characters of Rascal Does Not Dream of Bunny Girl Senpai are all affected by the rare and mysterious "Puberty Syndrome", which typically occurs when individuals experience high levels of stress or other negative emotions. For instance, the titular bunny girl is Mai Sakurajima, a girl who became invisible after wishing to be forgotten by the world.

In the case of Kaede Azusagawa, it is online bullying that causes her to lose her memories and gain a new personality. Yet even while her parents ignored her, unable to recognize their own daughter, her brother still reached out to her. Sakuta then became the only person Kaede could trust and rely on.

Fans of Rascal Does Not Dream of Bunny Girl Senpai should know that its creators also authored The Pet Girl of Sakurasou, another brilliant drama/romance title.

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5 Yuu & Ayumi Otosaka (Charlotte)

Original Series Produced by P.A. Works

Charlotte - Yuu & Ayumi Otosaka, and Nao Tomori having omurice together

The events of Charlotte take place in a seemingly ordinary boarding school, the Hoshinoumi Academy, whose secret purpose is to gather and protect adolescents who gained superhuman abilities because of the Charlotte meteor. All of the main characters have their unique abilities, with Yuu Otosaka's special skill being that of plundering others' abilities - although this is only revealed later in the show.

As for his sister Ayumi, her ability allows her to collapse everything around her, which she uses when threatened, resulting in her own death. Yuu is so affected by Ayumi's death that he experiences severe depression, but he eventually figures out a way to prevent it by time traveling.

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4 The Kawamato Sisters (March Comes In Like a Lion)

Produced by Shaft and Based on the Manga by Chica Umino

March Comes In Like a Lion Official Art, featuring Rei having coffee served by the cheerful Kawamoto sisters wearing maid uniforms

March Comes In Like a Lion follows Rei Kiriyama, a professional shogi player who decides to move to Tokyo alone to escape his troubled home life, but is unable to take care of himself due to struggling with mental health issues. Coming across the Kawamoto sisters by chance, Rei is saved by their warmth and welcoming nature, finding the family that he never had.

Despite having experienced tragedies of their own, Akari, Hinata, and Momo live a happy yet modest life, taking care of each other under any circumstances. Life may not have been easy for these sisters, but that only brought them closer together.

The creator of March Comes In Like a Lion also authored Honey and Clover, a similarly enjoyable tale of soul-searching, self-discovery, and human connections.

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3 Mirai & Yuuki Onozawa (Tokyo Magnitude 8.0)

Original Series Produced by Bones & Kinema Citrus

Mari, Mirai, and Yuuki walking down the street, holding hands

As one can surmise from the title, Tokyo Magnitude 8.0 explores the potential consequences of a magnitude 8.0 earthquake taking place in the Kanto region. The story follows Mirai Onozawa, a girl who reluctantly takes her younger brother, Yuuki, to Tokyo's artificial island, Odaiba, to attend a robot exhibition. The earthquake strikes during the exhibition, instantly crumbling buildings and changing the landscape of Tokyo.

Although she is initially annoyed by the idea of looking after her younger brother, Mirai eventually realizes just how important Yuuki is to her, as the two of them embark on a journey that changes their perspectives on life, alongside Mari Kusakabe, a single mother.

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2 Mutta & Hibito Nanba (Space Brothers)

Produced by A-1 Pictures and Based on the Manga by Chuuya Koyama

Space Brothers Nanba Mutta and Hibito standing in front of Earth, next to their childhood selves

Space Brothers revolves around the titular brothers, Mutta and Hibito Nanba, both of whom fell in love with space at a young age and vowed to become astronauts. Unfortunately, of the two, only Hibito, the younger brother, achieved his goals, while Mutta ended up working in an automotive company, only to be fired after defending Hibito.

Unexpectedly, this turn of events leads to him gaining the opportunity to participate in the next astronaut selection for JAXA, finally obtaining a chance to fulfill his childhood dream. Mutta and Hibito always had a good relationship, respecting and encouraging each other to keep going against all odds.

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Produced by Bones and Based on the Manga by Hiromu Arakawa

Alphonse and Edward Elric in a train in Fullmetal Alchemist Brotherhood

The events of the fan-favorite Fullmetal Alchemist: Brotherhood take place in a world where alchemy, despite being common, is bound by strict limitations and rules. The most important of all is the Law of Equivalent Exchange, according to which something of equal value must always be lost when creating something. Breaking this law by trying to resurrect their late mother, whose soul is unquantifiable, the brothers lose their bodies, either partially or fully, thereafter embarking on a quest to restore them.

Despite occasionally arguing due to their different personalities, Edward and Alphonse are also extremely protective of each other, and would sacrifice anything to save each other. Edward, especially, is driven to restore Alphonse's entire body, giving back his younger brother his humanity. Together with some of the most emotional plot twists in manga history, Ed and Al's relationship makes them stand out as some of the best siblings in anime.

Although it's quite different from Fullmetal Alchemist: Brotherhood, the creator also authored Silver Spoon, a genuinely worthwhile coming-of-age title.

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